besides, hes strong and healthy overall, maybe a little miserable at times but we could live with that. Does anyone else experience these symptoms? He is nibbling them constantly. I have had her since she was 6 mths old and she is now an old lady at 13. A dog who never once peed in the house, started having accidentswhen she was on a morning, noon, evening and bedtime schedule. Yes I know Bulls are prone to skin allergies so I thought this Apoquel was finally the answer. Can Apoquel be used with other medications? So in the midst of all of this I did notice that her pet food had changed gradually and I finally took the last case back and put her on another food just in case it was a food additive issue! DrugBank Accession Number. While still within reference ranges, mean serum globulin and mean white blood cell, It has now been 7 days since his last Apoquel dose, and while he can hold himself up, he is very wobbly and falls if he tries to run. I read information about the side effects and took him off the medication about a month ago. I noticed that he seemed a little lethargic after the first pill, but didnt feel alarmed since its supposed to do that. He also developed a TUMOR on this paw which my vet thought was malignant but fortunately it wasnt. Please never use acepromazine for dogs. In the summer when his allergic signs are more common, I am bathing him twice a week. In December 2017 we again returned to the veterinary center for evaluation and suggestions regarding these growths which continued to increase in number. The sedative properties are beneficial in these instances. How to Report Apoquel Side Effects in Dogs Apoquel side effects in dogs can be reported directly to the manufacturing company. Sadly, with the infections appearing after only a month on the drug, I felt in order to save her life, I had to take her off Apoquel, as I could only guess at the havoc she was going through internally from having her immune system suppressed. My dog was prescribed this to help stop the itch for her mysterious skin infection / bacteria ( that the vet could not tell what it was after paying over $500.00). She went from a healthy dog to a dog that was incontinent, drinking lots of water, getting us up in the night to go outside. Both Apoquel and Zyrtec are effective at relieving allergy symptoms in dogs, so combining them may provide even more relief for your dog. Thank you all for sharing. Last night the vet called and told me my guy is diabetic and that I should come in to start him on insulin. After allergy, blood and urine tests she put him on Apoquel, 2 times a day for 1 week and then one pill in morning. His spleen burst And blood was leaking into his abdomen they took blood and x-rays and found out that he had also cancer in his lungs, from the medication I would never put any dog on this medication ever and called the company and they still still will not say that the medication causes that issue even though he was healthy happy and the best dog and we had to put him to sleep at 4 1/2 years old due to him taking Apoquel. They assumed that he must have a tumor, so, we scheduled an Ultrasound. It also isnt working as well on her skin this time as it did when she was first on it. So Im not sure what to do. She is allergic to beef, flax, white potatoe, corn and a few other things. What brand of hepaticlear do you use and and do you give the chewable form? 5 days on Apoquel and she went to the kennel. If one person can try this and it helps your dog, I would be so happy for you and your dog. Not taking any chances! He is somewhat aggressive to a sweet little girl puppy that we got as a friend for him. After 3 days we stopped the medication because her organs were shutting down. Its the reason I looked this up and I am glad to know others have experienced this as well. The answer is no. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Zoetis, Apoquel's manufacturer, conducted a long-term (two year) study examining 247 dogs and the side effects of Apoquel they experienced. See what it can do for your dog here: http://www.thedogsupplement.com. Then he began acting weird one day starting with having diarrhea then he started panting, drooling, pacing, sitting on my chest I knew something was wrong and went to the animal emergency room. Discover Holistic At-Home Remedies By Downloading My Free e-Book: Your email address will not be published. My vet diagnosed him with 3 different bacterial infections which Im assuming he got from his immune system being compromised from this drug. Too few veterinarians are explaining the risks. You can check http://www.orthomolecular.org for more research and info. I am concerned because I keep discussing apoquel with multiple vets taking care of him and I am told that is not the cause of his acute illness. Early this morning he got out of bed, I thought he was getting a drink, he has always drank a lot of water. My 14 year old Boston Terrier.my best friend in the world had been plagued by itching his entire life. Benadryl is commonly used to treat itchiness in dogs caused by skin allergies, and it also reduces many of the other symptoms of allergies, including: Hives. 2 packs of apoquel tablets As always, you should talk to your veterinarian before starting your dog on any new medication, even if its something as seemingly innocuous as Benadryl or Zyrtec. She couldnt eat on her own and worst, she didnt recognize us or let us pet her. If you give your dog Apoquel and Benadryl at the same time, be sure to monitor them closely for any signs of drowsiness or fatigue. Yes, you can give your dog Apoquel and Zyrtec together. It was under the skin, wide but flat so it didnt show under his hair and wasnt obvious when patting him. This may inform but seems to be a scare tactic to sell his products. Zyrtec, or Cetirizine, is a popular method of itch relief in our canine friends due to how few side effects there are, and the fact that Zyrtec does not cause drowsiness like other allergy medications. I certainly want her to be happy but also healthy. Bit worried about that. Hydroxyzine belongs to a family of drugs called antihistamines. No more. Both hydroxyzine HCl (hydrochloride) and hydroxyzine pamoate have the same active ingredient, hydroxyzine. Its crazy how fast that can happen. With that, you will be able to give them the right dosage. Please, please be very cautious when using this drug on your babies.. Our dog Aries who is now 12 years old suffered with severe itching and allergic type reactions that appeared to start in 2016. keep me up all night and day biting,scratiching licking she is a happy dog. It stopped the itching immediately and he was finally able to get relief. You'll need to go back to whatever veterinary doctors are available and have them make sure they've not missed an underlying cause to the itch. Diagnosis is a mite type(Demoditic? However, after about a month and a half our four year old dog started vomiting and was extremely lethargic. He has urinated in front of me, also not wanting to stay outside, or even go outside. Your vet will determine which form will be the best way to treat your dog. I am a regular pet owner with a 10 year old staffy with chronic allergies, but I would NEVER in my life give this drug to my dog. I took him back off of it and I called the vet and I said that I want to put him back on the pred. If Zoetis produces the vaccines that were usedwell that would truly answer a lot of questions. require discontinuation of therapy. We will know more next week when the report comes back from histopatholgy. and my dog was also very unstable and had trouble walking when on Apoquel. Has been on short term antibiotics and steroids for secondary skin infections. Let him know that I would never give this precious dog any medication without our friends permission. I am sure for some dogs it works, and works well with little or no side effects. Hydroxyzine dosage for dogs. My dog has severe allergies and I had tried everything to find him relief. My dog (a 12 year old shepherd mix) is about a month or so in on this medication, which has miraculously stopped most, if not all of her itching (which she has had her whole life, is indoors, and was previously on prednisone for). I have to admit, I may be the only one in support of Apoquel. The girl has bladder trouble. The bonding after reviving her is incredibly tight. Does Apoquel interact with any medications? She sounds like a very sweet dog not making a mess for you. Lets have a look at how hydroxyzine is used to treat dogs. Sooooo happy with it but All of a sudden, she has developed a whole new set of even more significant and really scary issues: She started going kiki accidentally, when she would start digging on furniture, in bed, where ever! Its like there is flem in is throat and he cant catch his breath. Thankful that I followed my instinct as the vet made us very uncomfortable with his rapid sales pitch. Poor little guy. Just seems like a lot to me. My dog was recently given Apoquel for severe itching. Hello Dr I criticize but choose not to use my real name, This article is 100% based on FDA Veterinary ADE reports- you may want to visit the FDA site and read the stats for yourself. Being very worried, I began doing research on the Apoquel the vet had given her and was shocked to find out its an immunosuppressant with some ugly side effects. I feel apoquel has destroyed his ability to fight infections as before Ollie always responded well to treatments and now not at all. I was considering Apoquel for my 8 year old German Shepherd. After two months and weight gain and labored breathing on steroids Ollie still has this yeast infection. By example, many that are on chemo come to us for high dose IV vitamin C (50g-150g/infusion) Some dogs taking other types of antihistamines have also experienced vomiting. Apoquel also isn't recommended for dogs who have serious infections or for dogs who weigh less than 6.6 pounds. On the sixth day he could barely walk and we took him to an emergency vet hospital. Kelly would love to know what your experience was. A number of different antihistamines were used. Zyrtec, Claritin, and Benadryl are just some of the meds that both humans and dogs can take safely. He is still on hepaticlear..3 years later. I gave him a pill at 9 a.m. yesterday morning and another at 9 p.m. yesterday evening. It was a blistery, painful looking infection. She was totally out of it. Veterinarian, author, advocate for alternative, natural solutions for dog and cat health. We decided to continue the Apoquel until the next vet visit which was about 1 week later. Dogs under one year of age should not take Apoquel. Apoquel is an amazing Medication, I have a boston terrier and he has allergies to oak pollen and other blooming plants in the spring, he has been on apoquel severeal times throughout the past 2 years, for this condition, yes i have tried benydryl and he eats dog food with fish in it, by far apoqeul is the best medication to treat his allergies, no more itching, clear shiny coat again and is back to regular playful self, I give him 3.6 once a day and that does it, no side effects for Him. Who knows what would have happened if we continued another 2 weeks especially wth out dog being a senior. Use the best of all forms of proven, safe and effective methods to find underlying causes and correct them. I weaned her off the Hydroxyzine and started her on the Apoquel. His previous blood tests (before Apoquel) were normal. http://www.dogsnaturallymagazine.com/wouldnt-give-dog-new-allergy-drug/. Vets may prescribe it for both atopic dermatitis and allergic dermatitis - both problems that cause itchy and inflamed skin. Antihistamines work by blocking the action of histamines. 14 days later he died. This drug should be removed from the market. Never again will I use that drug. He sometimes paws at his bed at night and urinates like some of the pet owners stated above. I am grateful for tis kind of forum to be able to figure out what is wrong with our dog. At the beginning of Spring of this year. A lot of dog owners are asking how much Apoquel their dog can take. aday because of weight for 3 months now. Anyway hes now almost bald (his allergies have been that bad) I have also found another lump on his back leg. Both need to go out more often to pee. All of the sudden it clicked. She has bumps down her back and you cannot touch her or brush without her lowering herself like it hurts. 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