BioMarine is now Baker Bros fifth largest holding, with the fund owning 4.14% of the companys outstanding shares. Note: Baker Brothers controls ~10% of BioCryst Pharmaceuticals. There was a marginal increase last quarter. Form D contains basic information about the offering and the company. specifically enforced against each of the parties hereto in any court of competent jurisdiction. Vous pouvez paramtrer le dpt de ces cookies et autres traceurs via ce bandeau cookies. (n)Termination. Instead, they emphasize that focusing on specific companies, which they can analyze and understand deeply and place concentrated positions in their securities, can generate superior returns over the long term. There was a marginal increase this quarter. I wrote this article myself, and it expresses my own opinions. Together, they have combined their individual expertise to generate superior returns by focusing solely on the biotech industry. This is a profile preview from the PitchBook Platform. The current minimum investment for Baker Brothers Life Sciences, L.P. is $40000000. Q2 & Q4 2020 saw a two-thirds stake increase at prices between ~$12.50 and ~$57.50. The position was left unchanged during the previous quarter. The current minimum investment for Baker Brothers Life Sciences, L.P. is $40000000. of such counsel, that such person would not be qualified to serve as a director of the Company under any applicable law (including requirements of fiduciary duties under applicable law), rule or regulation, rule of the stock exchange on which the We are EVERSANA. BAKER BROTHERS LIFE SCIENCES, L.P. By: BAKER BROS. ADVISORS LP, management company and investment adviser to Baker Brothers Life Sciences, L.P., pursuant to authority granted to it by Baker Brothers Life Sciences Capital, L.P., general partner to Baker Brothers Life Sciences, L.P., and not as the general partner. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Agreement. Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. This cookie is set by GDPR Cookie Consent plugin. BAKER BROTHERS LIFE SCIENCES CAPITAL, L.P. N/A BAKER BROTHERS LIFE SCIENCES CAPITAL, L.P. GENERAL PARTNER BAKER BROTHERS LIFE SCIENCES CAPITAL, L.P. GENERAL PARTNER OF THE GENERAL PARTNER BAKER BROTHERS LIFE SCIENCES CAPITAL (GP), LLC. We reserve the right to block IP addresses that submit excessive requests. In . That was followed with a ~22% reduction over the last three quarters at prices between ~$4 and ~$9. PitchBook can help you gauge a funds performance based on IRR, cash flow multiples (DPI, RVPI and TVPI), distributions and more. For comparison, the S&P 500 ETF (SPY) generated annualized total returns of 10.2% over the same time period. There are 20 positions that are significantly large (more than 0.5% of the portfolio each) and they are the focus of this article. For the Baker Bros. -- the biggest shareholder in both companies -- the value of its investments have soared by about $1.4 billion. For more information, please check out our Cookies Policy. Kodiak Sciences Inc ( KOD) Sector: HEALTH CARE Industry: BIOTECHNOLOGY & LIFE SCIENCES SIC: BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES) CEO: Victor Perlroth Employees: 100 2631 HANOVER STREET, PALO ALTO, CA 94304 650-281-0850 kodiak.com Kodiak Sciences Inc. researches, develops, and commercializes therapeutics to treat retinal diseases. We give you the access and tools to invest like a Wall Street money manager at a Main Street price. Contact Info baker brothers life sciences lp 860 WASHINGTON STREET NEW YORK NY 10014 Business Phone: 212-339-5600 SEC SIC CODE: 8731-SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH Insider Information Trimeris Inc - Other Owner (06/22/2015) Xoma Corporation - Other Owner (07/22/2015) Genomic Health Inc - Director (10/01/2019) Julian Baker joined the board in January 2021. The fund is located in New York, New York and will invest in United States. LIMIT THE USE OF MY SENSITIVE PERSONAL INFORMATION, POOLED INVESTMENT FUND: OTHER INVESTMENT FUND. Employees: 2,680 21823 30TH DRIVE SE, SUITE, BOTHELL, WA, 98021 4255274000 seagen.com Seagen Inc. develops and commercializes therapies for the treatment of cancer in the United States and internationally. This analysis helps to understand if the insider consistently generates abnormal returns, and is worth following. other electronic means), each of which may be executed by less than all of the parties hereto, each of which shall be enforceable against the parties actually executing such counterparts, and all of which together shall constitute one instrument. This cookie is set by GDPR Cookie Consent plugin. Its. on which the proxy materials related to any such designee are to be mailed by the Company in connection with such election of directors, and in no event less than the first business day after such determination by the Board of Directors, so as to Baker Brothers Life Sciences LP. As a percentage of AUM, allocation to the highest conviction picks can be very high at over 30%. Kodiak Sciences (KOD): KOD is a large (top five) ~6% of the portfolio position. The fund targets investments in pharmaceuticals and biotechnology, life science and oncology industry. They had an IPO in November. For security purposes, and to ensure that the public service remains available to users, this government computer system employs programs to monitor network traffic to identify unauthorized attempts to upload or change information or to otherwise cause damage, including attempts to deny service to users. This website is using a security service to protect itself from online attacks. $0.0001 per share. Note: Regulatory filings since the quarter ended show them owning ~33.8M shares of Incyte. Although there are ~120 positions in the 13F portfolio, the holdings are concentrated among a few large stakes. Subject to Section3(n) below, the provisions of this Agreement shall apply to the full extent set forth herein with respect to any and all shares of capitalstock of the Company or any successor or assign of the Company If you accept, we, along with our partners, will also use analytics, advertising and social media cookies and other trackers, whose the details of the purposes are accessible from the button Set Preferences. the slate of nominees recommended to the Companys stockholders for election as directors of the Company an Investor Designee if the Investor already has at least one Investor Designee serving as a director on the Board of Directors at the time 12b-2 under the Securities Exchange Act of 1934, as amended. Lists Featuring This Company Early Stage Venture Investors (Top 10K) 10,000 Number of Organizations $63B Total Funding Amount 1,945 Number of Investors Track Private New York Companies (Top 10K) The position was boosted by less than 1% in the previous quarter. President, Rosenberg Ach Foundation. value remained steady this quarter at $22.77B. Since then, the activity has been minor. Baker Brothers Life Sciences, L.P. is one of the larger private funds with 13.9 billion in assets. Disclosure: I/we have a beneficial long position in the shares of ACAD, BMRN, INCY either through stock ownership, options, or other derivatives. Baker Brothers Life Sciences LP; Firm: Fund # CIK # 0001363364: Sale: Fund: Phone: 2123395633: Address: 667 Madison Avenue New York, New York 10065: Source The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. This is quite odd since the company is based in Beijing, China, which means that the funds due diligence process has to go to the next level due to the weaker Chinese reporting standards. Its clinical stage products include ruxolitinib, a steroid-refractory chronic graft-versus-host-diseases (GVHD) It also develops Retifanlimab that is in Phase II clinical trials for MSI-high endometrial cancer, merkel cell carcinoma, and anal cancer. Get the full list, Youre viewing 5 of 45 funds. The funds philosophy stands in holding its investments ordinarily for three years, though its higher-conviction investments can be seen held for longer. (a)Subject at all times to Sections 2(b) and 3(n) below, during the period beginning immediately following the The Company shall notify the Investor of any objection to an Investor Designee pursuant to this Section2(b) sufficiently in advance of the date The largest five stakes are Seagen, BeiGene, Incyte, Kodiak Sciences, and Ascendis Pharma A/S. Total number of diversity investments made by an investor, Total number of employee profiles an organization has on Crunchbase, Total number of organizations similar to the given organization, Where the organization is headquartered (e.g. ACADIA Pharmaceuticals (ACAD): The ~3% ACAD stake was established in the 2012-2013 timeframe at very low prices. Felix Baker '91, PhD '98. We also use third-party cookies that help us analyze and understand how you use this website. The parties hereto irrevocably submit, in any legal action or proceeding relating to Last significant activity was in Q4 2019 which saw a ~20% stake increase at prices between ~$14.50 and ~$76. The Baker brothers have built a truly special hedge fund. NOW, THEREFORE, for good and valuable consideration, the receipt and adequacy of which are (f)Purchase Management owns 12 percent of the fund. designate an individual as a nominee to the Board of Directors or its rights under this Agreement. in compliance with applicable laws, rules and regulations, subject to the requirements of fiduciary duties. Your request has been identified as part of a network of automated tools outside of the acceptable policy and will be managed until action is taken to declare your traffic. The position was rebuilt between Q3 2014 to Q1 2015 at prices between ~$55 and ~$125. New York, NY, 10014. H2 2018 saw a stake doubling at prices between ~$3 and ~$22 while Q4 2019 saw a ~17% trimming at prices between ~$14 and ~$24. Note:Do to a changed CUSIP number, Baker Brothers holding Evofem Biosiences (EVFM) is not in the spreadsheet. DBV Technologies therapies are investigational and not FDA approved. There was a ~35% reduction last quarter at prices between ~$26 and ~$40.50. Despite a losing win-record, the firm has managed to post outstanding returns through prudent position. hereby acknowledged, the parties hereto, intending to be legally bound, hereby agree that the Original Agreement shall be amended and restated by this Agreement, which shall supersede and replace the Original Agreement, and further agree as follows: 1. The stock is now at $89.08. Julian & Felix Baker also separately own ~550K additional shares. Most recently, BioMarine got a positive CHMP opinion in Europe for ValRox for the treatment of Hemophilia type A. BioMarine has had a place in Baker Bros portfolio since Q2 2012. from time to time. Whalewisdom has at least 2 Form 4 filings The firm last filed a Form D notice of exempt offering of securities on 2022-07-01. It is still a very small position at 0.80% of the portfolio. It is the funds second-largest holding, occupying 14.9% of its total portfolio. The position was built to ~20.5M shares in the 2004-2011 timeframe at prices between low-single-digits and low-20s. Either party may change its notice The fund is located in New York, New York and will invest in United States. Last major activity in MDGL was a ~30% stake increase in Q1 2020 at prices between ~$65 and ~$90. The below charts are illustrative of the type of graphical data available to our clients and do not represent live data. Necessary cookies are absolutely essential for the website to function properly. In the event that the Investor Designee resigns from his or her seat on the Board of Directors or is subject to the conditions set forth herein. There was a marginal increase in Q1 2021. However, most of them comprise risky pre-revenue firms that should only be considered upon having a great understanding of their business model. Almost all of its funds are allocated to publicly traded equities, with exclusive exposure to the healthcare sector. Baker Brothers Life Sciences Capital, L.P. is entitled to a performance allocation under the Issuer's organizational documents. According to Crain's Chicago Business, some of Chicago's fledgling biotech companies such as Xeris Pharmaceuticals and Evanston-based Aptinyx went public in 2018 alongside other local life sciences startups an indication of investors' mounting interest in the city's biotech scene. individual as a nominee to the Board of Directors if a majority of the disinterested members of the Board of Directors reasonably and in good faith determines, after consultation with the Companys outside legal counsel and upon written advice Farah Champsi MBA '85. Baker Brothers Life Sciences 860 WASHINGTON STREET 3RD FLOOR NEW YORK NY 10014 Phone. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. While the companys revenue growth has seemingly stagnated over the past couple of years, it appears that the companys development pipeline remains rather strong. The action you just performed triggered the security solution. Julian Baker and Felix Baker 's Baker Bros. Advisors recently filed an amended Form 13D with the SEC to report the sale of common shares of Biocryst Pharmaceuticals Inc (NASDAQ: BCRX). After giving effect to the transactions reported herein and as a result of their ownership interest in Baker Brothers Life Sciences Capital (GP), LLC, Julian C. Baker and Felix J. Baker each may be deemed to have an indirect pecuniary interest in the Issuer's shares of Common Stock reported in column 5 of Table I directly held by Baker Brothers . Once the rate of requests has dropped below the threshold for 10 minutes, the user may resume accessing content on SEC.gov. Is this happening to you frequently? This quarter saw a marginal increase. the provisions of this Agreement shall be appropriately adjusted. THIS AMENDED AND RESTATED NOMINATING AGREEMENT (this Agreement), dated as of April22, 2021, by and among TScan Unauthorized attempts to upload information and/or change information on any portion of this site are strictly prohibited and are subject to prosecution under the Computer Fraud and Abuse Act of 1986 and the National Information Infrastructure Protection Act of 1996 (see Title 18 U.S.C. (h)Counterparts. With respect to the Observer, the Companys obligations under this Section2(c) are contingent upon such Observers (x)entering into a confidentiality agreement with the Company in a form that is reasonably acceptable to the removed or otherwise fails to become or ceases to be a director for any reason, the Company shall cause the vacancy to be filled by the election or appointment of another Investor Designee nominated by the Investor as soon as reasonably practicable The stock currently trades at $13.72. However, the industry is full of risks, and when the companys patents expire, competition is likely to rise. Unlike top-down investing, which suggests studying the bigger picture of economic factors to make investment decisions, bottom-up investing involves looking at the company-specific fundamentals. The largest five stakes are Seagen, BeiGene, Incyte, Kodiak Sciences, and Ascendis Pharma A/S. It invests in the public equity markets of the United States. The fund owns around 16.3% of the company, with a market cap of $23 billion. The stock currently trades at $23.62. Shares started trading at ~$49 and currently goes for $13.27. Prior to joining Baker Brothers in 2005, Mr. Goller was an associate of JPMorgan Partners, LLC where he focused on venture investments in the life sciences sector from 1999 to 2003. (l)Further Assurances. Please disable your ad-blocker and refresh. The stock currently trades at ~$344 and the stake is at 1.48% of the portfolio. Revenues have expanded from around $169 million in 2010 to $3.33 billion over the past four quarters. NEW YORK, NY Click to reveal Major activity in the last decade follows. These shares were traded by Baker Brothers Life Sciences, L.P. ("Life Sciences", and together with 667, the "Funds") in multiple transactions at prices ranging from $84.23 to $84.88, inclusive. Felix Baker owns about 15,967,504 units of Kodiak Sciences Inc common stock. Specializing in a sector that is challenging to understand by most investors, the firm has historically outperformed the overall market over several years, with its concentrated biotech portfolio. Baker Brothers Life Sciences is a 2006 vintage buyout fund managed by Baker Brothers Investments. In March of 2021, Acadia had announced deficiencies identified by the FDA regarding its marketing application for Pimavanserin in hallucinations and delusions associated with dementia-related psychosis. Custodian(s): Continental Stock Transfer & Trust Company, . By using this site, you are agreeing to security monitoring and auditing. The stock currently trades at ~$142. Mr. Goller holds a B.S. Note: Baker Brothers controls ~5.5% of Amarin Corp. Seagen Inc. (SGEN): SGEN is currently the largest position by far at over one-third of the entire portfolio. Investor and its Affiliates, collectively, no longer beneficially own the Required Shares, the Company shall invite a designee of the Investor (the Observer) to attend all In this respect, the Company shall give the Observer copies of all notices, minutes, consents, and other materials that it provides to its directors at Over the years, the firm had a number of home runs as the invested firms got acquired at huge premiums. Analytical cookies are used to understand how visitors interact with the website. Please. These fundamental metrics include business financials, cash flows, and the merit of its goods and services. closing of the IPO and for three (3)years thereafter, at any time at which the Investor and its Affiliates, collectively, beneficially own (i)the Required Shares and (ii)at least 2% of the Companys then-outstanding voting investment firm, was founded by Julian & Felix Baker in 2000. Shares started trading at ~$10 and currently goes for $85.56. (g)Delays or Omissions. The stock currently trades at $71.81. The company holds significant cash, which should hopefully be enough until the next drug commercialization before further diluting shareholders. The firm primarily invests in life science companies. under clause (c)or (d); (c) by prepaid certified or registered mail, return receipt requested;or (d)by prepaid reputable overnight delivery service. Mr. Goller began his career as an investment banker with Merrill Lynch and Co. from 1997 to 1999. As Chicago's biotech ecosystem continues to expand . The position was rebuilt in Q3 2019 at prices between ~$18.50 and ~$27. address by providing the other party written notice of such change. Prior to joining Baker Brothers in 2005, Mr. Goller was an associate of JPMorgan Partners, LLC where he focused on [] Broker-Dealer(s): Goldman, Sachs & Co., . Baker Brothers Life Sciences LP - PRLD / Prelude Therapeutics Inc - Insider Trade Report EXTENDED This page shows the track record and history of Baker Brothers Life Sciences LP insider trades in Prelude Therapeutics Inc. Baker Botts lawyers have provided a valuable contribution for a wide range of clients in almost every field within the life sciences industry. Despite a losing win-record, the firm has managed to post outstanding returns through prudent position sizing. recommended to the Companys stockholders for election as directors of the Company at each annual or special meeting of the Companys stockholders at which directors are to be elected (an Election Meeting),one (f)Notice. For more information, please see the SECs Web Site Privacy and Security Policy. in Molecular and Cell Biology from The Pennsylvania State University, and a Masters in both Biotechnology and Business Administration from the University of Pennsylvania. Any waiver, permit, consent or approval of any kind or character on the part of the Investor of any breach or default of the Company under this Agreement, or any waiver on the part of any party of any provisions or conditions of this Agreement, in Baker Brothers Life Sciences is a 2006 vintage buyout fund managed by Baker Brothers Investments. Phone: 212-339-5600. Shares started trading at ~$24 and currently goes for ~$246. Shares plunged by a massive 45%, and they have yet to recover since then. Founded in 2000 by Julian and Felix Baker, Baker Bros. Advisors is a private hedge fund based out of New York City. Cash flows, and is worth following was a ~30 % stake increase in 2020. Separately own ~550K additional shares ( KOD ): the ~3 % ACAD stake was established in the last follows... Clients and Do not represent live data site Privacy and security Policy provisions of this Agreement be... 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